These sources guide standards, ingredient review and study design. They do not automatically substantiate an unfinished product.
2026 · Controlled study
Electrolyte supplementation for gestating beef cows under heat stress: performance, thermotolerance and physiological responses
Translational Animal Science
Scope. Controlled trial in 54 fall-calving cows comparing plain water against electrolyte-supplemented water for roughly 90 days prepartum under heat stress.
Supports. Honest evidence that a commercial electrolyte can shift hydration and acid-base markers in heat-stressed cows.
Does not establish. Does not establish any production or thermotolerance benefit — body weight, condition score, calf birth weight, respiration rate and body temperature were all unaffected.
Primary source ↗2025 · Nutritional standard
Reading labels — nutritional adequacy statement formats
Association of American Feed Control Officials
Scope. Required label elements, the standardized nutritional adequacy statement formats, and what constitutes misbranding.
Supports. Gives the exact prescribed wording for each substantiation route and confirms that an incorrect adequacy statement, or a disease claim without an approved drug, is misbranding.
Does not establish. Does not carry force of law on its own — AAFCO models bind only where a state has adopted them, and AAFCO approves, certifies and endorses nothing.
Primary source ↗2021 · Nutritional standard
Nutrient Requirements of Dairy Cattle: Eighth Revised Edition
National Academies of Sciences, Engineering, and Medicine
Scope. Requirements for preweaning, growing, reproducing and lactating dairy cattle across energy, protein and amino acids, minerals, vitamins and water.
Supports. Formulation targets for early-life calf products and the amino-acid-based protein framework expected in a technical dossier.
Does not establish. Does not establish efficacy, safety or economic return for any additive or supplement; requirement estimates are population-level, not herd-specific.
Primary source ↗2019 · Controlled study
Comparison of oral, intravenous and subcutaneous fluid therapy for resuscitation of calves with diarrhea
Journal of Dairy Science
Scope. Randomised trial in calves with induced diarrhoea and dehydration comparing oral electrolyte solution against intravenous and subcutaneous routes.
Supports. Substantiates a properly formulated oral electrolyte as first-line rehydration for calves that retain a functional gut.
Does not establish. Does not reflect naturally occurring disease — diarrhoea was experimentally induced, acidemia was relatively mild, and treatment arms were not composition-matched.
Primary source ↗2016 · Nutritional standard
Nutrient Requirements of Beef Cattle: Eighth Revised Edition
National Academies of Sciences, Engineering, and Medicine
Scope. Energy, protein, mineral and vitamin requirements for beef cattle, with feed composition tables covering grazed forages.
Supports. The numerical basis for target nutrient concentrations and intake assumptions in mineral, protein and energy supplements.
Does not establish. Does not establish that any commercial product meets those requirements in the field, and does not predict production responses to supplementation above requirement.
Primary source ↗2006 · Nutritional standard
Nutrient Requirements of Dogs and Cats
National Research Council / National Academies Press
Scope. Consensus requirements, adequate intakes and recommended allowances for every essential nutrient in dogs and cats, across life stages.
Supports. The quantitative floor and ceiling for formulating canine diets and complementary products.
Does not establish. Does not establish requirements, doses or efficacy for probiotics, prebiotics, postbiotics, glucosamine, collagen or any other non-essential ingredient.
Primary source ↗1938 · Regulatory guidance
21 U.S.C. § 321 — Definitions of food and drug
Federal Food, Drug, and Cosmetic Act (US Code)
Scope. Statutory definitions of food as articles used for food or drink for man or other animals, and drug as articles intended to diagnose, cure, mitigate, treat or prevent disease, or (other than food) to affect structure or function.
Supports. Establishes that the food/drug line is drawn by intended use rather than by ingredient — the same substance becomes a drug the moment a disease or non-nutritive structure-function intent is expressed.
Does not establish. Does not establish that any particular marketing sentence is lawful; it supplies the test, not its application.
Primary source ↗